RTS-8, Multi-channel Bioreactor with non-invasive real time biomass, pH and pO2 measurement

Description

RTS-8 is a personal bioreactor that utilizes patented Reverse-Spin® technology that applies non-invasive, mechanically driven, low energy consumption, innovative type of agitation where cell suspension is mixed by the single-use falcon bioreactor tube rotation around its axis with a change of direction of rotation motion resulting in highly efficient mixing and oxygenation for aerobic cultivation. Combined with a nearinfrared optical system it is possible to register cell growth kinetics non-invasively in real time.

FEATURES

  • Parallel cultivation enables to save time and resources for bioprocess optimization
  • Individually controlled bioreactor accelerates optimization process
  • Possibility to cultivate microaerophilic and obligate anaerobic microorganisms (not strict anaerobic conditions)
  • Reverse–Spin® mixing principle enables non-invasive biomass measurement in real time
  • Near-infrared optical system makes it possible to register cell growth kinetics
  • Free of charge software for storage, demonstration and analysis of data in real time
  • Compact design with low profile and small footprint for personal application
  • Temperature control for bioprocess applications
  • Active cooling for rapid temperature control, e.g. for temperature fluctuation experiments
  • Task profiling for process automatization
  • Cloud data storage to remotely monitor the process of cultivation while at home or using a mobile phone


SOFTWARE FEATURES

  • Real–Time cell growth logging
  • 3D graphical representation of OD or growth rate over time over unit
  • Pause option
  • Save/Load option
  • Report option: PDF and Excel
  • Connect up to 12 units (recommended) simultaneously to 1 computer
  • Remote monitoring option (requires internet connection)
  • Cycling/Profiling options
  • User manual calibration possibility for most cells


TYPICAL APPLICATIONS

  • Fermentation real time growth kinetics
  • Clone candidate screening
  • Protein expression
  • Temperature stress and fluctuation experiments
  • Media screening and optimization
  • Growth characterization
  • Inhibition and toxicity tests
  • Strain quality control

Specification

Measurement range 0-100 OD600
Measurement wavelength (λ) 850 ± 15 nm
Light source Laser
Measurement periodicity per hour 1-60
Temperature setting range +4°C ... +60°C
Temperature control range 15°C below ambient ... +60°C
Heating/coolling rate 0.5 °C/min
Sample volume 3–50 ml
Speed control range 50–2,700 rpm
Max. number of units connected to the software 12 (recommended)
Display LCD
Minimum PC requirements Intel/AMD Processor, 1 GB RAM, Windows XP*/Vista/7/8/8.1, 2.0 USB port
Optimal PC requirements Intel/AMD Processor, 3 GB RAM Windows XP*/Vista/7/8/8.1/10, USB 2.0 port

* not guaranteed because OS not supported by producer
Dimensions (W×D×H) 330 × 580 × 320 mm
Weight 15 kg
Internal power supply Input AC 100–240 V 50/60 Hz; Output DC 12 V
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02 sensor +
Range 0-100%
Accuracy ± 0.01% O2 at 0.21%, ± 0.1% O2 at 20.9%
Drift < 0.015% O2 per Day
Temperature range up to 40°C
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pH sensor +
Range pH 4.0 - pH 8.5
Accuracy ± 0.05 pH at pH 7 with one-point calibration, ± 0.10 pH at pH 7 with precalibration
Drift < 0.005 pH per day
Temperature range pH up to 40°C

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